Laboratory
of
Motivation
and Memory
Exploring the connections between neural circuits and behavior
People
The Lin lab is proud to have a group of creative, curious, and passionate scientists. They make the Lin lab a unique place to work and enjoy science. Each of us is tackling different scientific questions. Together, we hope to establish detailed cellular and molecular understandings for how complex neural circuits in the brain are assembled and how these circuits integrate and compute information to produce proper behavioral decisions.
News
Lin lab climbed Keelung Mt.
March 6, 2023
The Lin Lab took a delightful spring outing to Juifen (九份) and had an exhilarating climb up Keelung Mountain. The weather was perfect, the scenery was beautiful, and the food at 星塵景觀餐廳 was delicious!
Suewei is awarded NSTC Outstanding Research Award
February 27, 2023
Dr. Suewei Lin has been awarded the Outstanding Research Award by the National Science and Technology Council. This achievement is a testament to the incredible efforts of every member of the Lin Lab. Congratulations to the team!
Jasmin passed the qualifying exam
February 23, 2023
Congratulation to Jasmin on passing her qualifying exam and becoming a Ph.D. candidate! A milestone achieved!
Publications
Lin S. (2023 Jan) The making of the Drosophila Mushroom Body. Front Physiol 14:1091248
Bansal S, Lin S. (2023 Jan) Transcriptional Genetically Encoded Calcium Indicators in Drosophila. Cold Spring Harb Protoc 2023(1):pdb.top107797
Bansal S, Lin S. (2023 Jan) Imaging CaLexA and TRIC signals in the dissected fly central nervous system. Cold Spring Harb Protoc 2023(1):pdb.top108049
Lin CH, Senapati B, Chen WJ, Bansal S, Lin S. (2022, Mar) Semaphorin 1a-mediated dendritic wiring of the Drosophila mushroom body extrinsic neurons. Proc. Natl. Acad. Sci. USA 119(12):e2111283119.
Yang M, Chen C, Zhang S, Wang H, Wang M, Li S, Senapati B, Yi S, Wang L, Cheng J, Zhang M, Yin S, He Y, Lin S, Xue L, Ho MS. (2021, Jun) Glia-derived temporal signals orchestrate neurogenesis in the Drosophila mushroom body. Proc. Natl. Acad. Sci. USA 118(23):e2020098118.
Senapati B, Tsao CH, Juan YA, Chiu TH, Wu CL, Waddell S, Lin S. (2019) A neural mechanism for deprivation state-specific expression of relevant memories in Drosophila. Nature Neurosci 22(12):2029-2039
Lin S, Senapati B, Tsao CH. (2019) Neural basis of hunger-driven behaviour in Drosophila. Open Biology 9(3):180259
Tsao CH, Chen CC, Lin CH, Yang HY, Lin S. (2018) Drosophila mushroom boides integrate hunger and satiety signals to control innate food-seeking behavior. eLife 7:e35624
Felsenberg J, Barnstedt O, Cognigni P, Lin S, Waddell S. (2017) Re-evaluation of learned information in Drosophila. Nature 544(7649):240-244
Das G, Lin S, Waddell S. (2016) Remembering Components of Food in Drosophila. Front Integr Neurosci. 19;10:4
Owald D, Lin S, Waddell S. (2015) Light, heat, action: neural control of fruit fly behaviour. Phials Trans R Soc Lond B Biol Sci. 379(1677): 20140211
Huetteroth W, Perisse E, Lin S, Klappenback M, Burke C, Waddell S. (2015) Sweet taste and nutrient value subdivide rewarding dopaminergic neurons in Drosophila. Curr Biol 25(6):751-758
Lin S, Owald D, Chandra V, Talbot C, Huetteroth W, Waddell S. (2014) Neural correlates of water reward in thirsty Drosophila. Nat Neurosci 17:1536-1542
Lin S, Marin EC, Yang CP, Kao CF, Apenteng BA, Huang Y, O'Connor MB, Truman JW, Lee T. (2013) Extremes of Lineage Plasticity in the Drosophila Brain. Curr Biol 23:1908-1913
Perisse E, Yin Y, Lin AC, Lin S, Huetteroth W, Waddell S. (2013) Different kenyon cell populations drive learned approach and avoidance in Drosophila. Neuron 79:945-956
Lin S, Kao CF, Yu HH, Huang Y, Lee T. (2012) Lineage analysis of Drosophila lateral antennal lobe neurons reveals Notch-dependent binary temporal fate decisions. PLoS Biol 10(11): e1001425
Lin S, Lee T. (2012) Generating neuronal diversity in the Drosophila central nervous system. Dev Dyn 241:57-68
Lin S, Lai SL, Yu HH, Chihara T, Luo L, Lee T. (2010) Lineage-specific effects of Notch/Numb signaling in post-embryonic development of the Drosophila brain. Development 137:43-51
Lin S, Huang Y, Lee T. (2009) Nuclear receptor Unfulfilled regulates axonal guidance and cell identity of Drosophila mushroom body neurons. PLoS One 4:e8392
Chen YC, Lin S, Chen YK, Chiang CS, Liaw, GJ. (2009) The torso signaling pathway modulates a dual transcriptional switch to regulate tailless expression. Nucleic Acid Res 37:1061-1072
Lei S*, Lin S*, Grinberg Y, Beck Y, Grozinger CM, Robinson GE, Lee T. (2007) Roles of Drosophila Kruppel-homolog 1 in neuronal morphogenesis. Dev Neurobiol 67:1614-1626
Zhu S, Lin S, Kao CF, Awasaki T, Chiang AS, Lee T. (2006) Gradients of the Drosophila Chinmo BTB-zinc finger protein govern neuronal temporal identity. Cell 127:409-422
Wang J, Lee CH, Lin S, Lee T. (2006) Steroid hormone-dependent transformation of polyhomeotic mutant neurons in the Drosophila brain. Development 133:1231-1240.